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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Characterization of receptor tyrosine kinase activation and biological activity of toceranib phosphate in canine urothelial carcinoma cell lines

Fig. 2

Phospho-RTK array profiling of primary canine UC tumors. Shown are representative examples of phosphoprotein arrays of primary UC tumors using the Proteome Profiler Human Phospho-RTK Array Kit. This assay allows for the simultaneous screening of 42 different RTKs. Determination of phosphorylation was based on comparison of capture antibody of interest to positive controls (red arrows) located on the periphery of the array. On these sample arrays, positive control EGFR has been identified for comparison. RTKs targeted by toceranib phosphate, PDGFRα, PDGFRβ, and VEGFR2 are indicated in the figure legend

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BMC Veterinary Research

ISSN: 1746-6148

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