Fig. 1

Laparoscopy, histopathology, and computed tomography angiography images from an American Cocker Spaniel on day 3. The micronodular formation (arrows) on the surface of atrophied left liver lobes (A) and the development of acquired portosystemic collaterals (arrow heads) around the area of the left kidney were observed using a 5-mm palpation probe (B). The normal liver architecture was disrupted by diffuse infiltration of hyperplastic bile ducts and inflammatory cells (asterisk) in the hepatic parenchyma, and some regenerative nodules were present on histopathology, hematoxylin and eosin stain (C). No evidence of a thrombus was found in the portal vein using computed tomographic angiography (D). A, ascites; Ao, aorta; CVC, caudal vena cava; K, kidney; L, liver; P, palpation probe; PV, portal vein