Early detection of myocardial dysfunction in a cat that gradually progressed to endomyocardial form of restrictive cardiomyopathy

Table 1 Conventional echocardiographic variables at first visit (day 0) and follow-up examinations

	Day 0	Day 89	Day 468	Healthy cats
Echocardiograohic variables
End-diastolic IVS thickness (mm)	5.9^a	5.1^a	5.4^a	3.8 (3.4, 4.1)
End-diastolic LV free wall thickness (mm)	3.7	3.3^a	3.3^a	4.2 (3.6, 4.3)
End-diastolic LV internal dimension (mm)	14.7	17.3^a	18.5^a	14.0 (13.5, 15.5)
End-systolic LV internal dimension (mm)	6.8	7.6	11.5^a	7.2 (6.4, 8.9)
Fractional shortening (%)	53.8^a	56.1^a	37.8^a	49.1 (40.8, 53.1)
LA diameter (mm)	14.3	15.2	19.0	10.9 (9.7, 11.9)
LA to aortic root diameter ratio	1.5^a	1.5^a	2.2^a	1.3 (1.2, 1.4)
E velocity (m/s)	0.46^a	0.50^a	0.65 (fused)	0.60 (0.57, 0.73)
A velocity (m/s)	0.71	0.64		0.69 (0.57, 0.73)
E/A	0.6^a	0.8		0.9 (0.8, 1.2)
S' (cm/s)	4.9^a	7.7	9.3	8.0 (6.9, 10.5)
E' (cm/s)	11.2^a	5.8	4.4^a	7.0 (5.1, 7.6)
Systolic blood pressure (mmHg)	125	135	133	140 (125, 149)

Healthy cat ranges (median [interquartile range]) were established from 15 healthy cats
A Late-diastolic trans-mitral flow velocity, E Early-diastolic trans-mitral flow velocity, E’ myocardial velocity of the septal mitral annulus at early-diastole, IVS interventricular septum, LA left atrium, LV left ventricular, S’ myocardial velocity of the septal mitral annulus at systole
^aValue that was out of the interquartile range of the 15 healthy cats

ISSN: 1746-6148