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Table 2 Comparison of C. psittaci LAMP assays using rapidly processed swab samples

From: Real-time fluorometric and end-point colorimetric isothermal assays for detection of equine pathogens C. psittaci and equine herpes virus 1: validation, comparison and application at the point of care

C. psittaci cLAMP# C. psittaci rtLAMP
  Positive Negative Total
Positive 6 2 8
Negative 0 26 26
Total 6 28 34
Kappa (0.95 CI; p(Kappa)) 0.821 (0.584–1.06; 0.00)
McNemar’s Chi square (p(Chi sq)) 0.500 (0.479)
Overall agreement b 94.12% (85.71% PA; 96.30% NA)
C. psittaci sgLAMP C. psittaci rtLAMP
  Positive Negative Total
Positive 6 1 7
Negative 0 29 29
Total 6 30 36
Kappa (0.95 CI; p(Kappa)) 0.906 (0.726–1.09; 0.00)
McNemar’s Chi square (p(Chi sq)) 0.000 (1.00)
Overall agreement b 97.22% (92.31% PA; 98.31% NA)
C. psittaci sgLAMP C. psittaci cLAMP#
  Positive Negative Total
Positive 6 1 7
Negative 2 25 27
Total 8 26 34
Kappa (0.95 CI; p(Kappa)) 0.744 (0.471–1.017; 0.00)
McNemar’s Chi square (p(Chi sq)) 0.000 (1.00)
Overall agreement b 91.18% (80.00% PA; 94.34% NA)
  1. #: two samples were excluded from analyses as immediate discoloration of the mix (to yellow and/or orange) was observed upon addition the swab suspension; b: positive agreement (PA) and negative agreement (NA) are outlined in brackets