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Table 1 Effects of donkey-derived IgG on clinical symptoms of the CDV-infected dogs at the different time

From: Donkey-derived anti-CDV IgG, as a passive immunotherapy agent, can effectively increase survival rates of the experimental CDV-infected dogs

Symptoms Time after CDV infection (d)
CDV CDV + Donkey IgG CDV + Dog IgG
2–3 5–6 8–9 11–12 14–15 2–3 5–6 8–9 11–12 14–15 2–3 5–6 8–9 11–12 14–15
Loss of appetite + +++ ++ +++ +++ + ++ ++ ++ + + ++ ++ + +
Gum in the eyes +++ ++ +++ +++ ++ + + + + +
Running at the nose +++ ++ +++ +++ ++ + + ++ + +
Cough ++ + +++ +++ + + + + +
Diarrhea/dehydration ++ + +++ +++ + + +
Neurologic symptom ++ +++
  1. +, ++ and +++ respectively represent the severity of symptoms: mild, moderate and severe