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Fig. 5 | BMC Veterinary Research

Fig. 5

From: The antiviral activity of kaempferol against pseudorabies virus in mice

Fig. 5

Histopathological examination of the tissues including heart, liver and spleen on 5dpi. In the heart (A-F), PRV infection causes breakage of myocardial fibers and disordered arrangement (denoted by arrowhead “←”), the blood vessel wall of the heart appears shedding to varying degrees (denoted by arrowhead “→”), and localized vacuolar degeneration (denoted by arrowhead “↑”). In the liver (G-L), the main histopathological changes are shedding of blood vessel walls (denoted by arrowhead “←”), disordered arrangement of hepatic cords (denoted by arrowhead “→”), hepatocellular swelling (denoted by arrowhead “↓”), and foam-like changes (denoted by arrowhead “↑”). In the spleen (M-R), the lesions showed a decrease in the area of the red pulp area (denoted by arrowhead “←”) and white pulp area (denoted by arrowhead “→”), vacuolar degeneration (denoted by arrowhead “↑”). In the lung (S-X), the main lesions included bleeding (denoted by arrowhead “←”), alveolar septal rupture and thickening (denoted by arrowhead “→”), inflammatory cell infiltration (denoted by arrowhead “↓”). In the kidney (Y-ZD), the lesions mainly included hyperemia in the cortical area (denoted by arrowhead “←”) and medulla area (denoted by arrowhead “→”), shedding of renal tubular epithelial cells and glomerular swelling (denoted by arrowhead “↓”). In the brain (ZE-ZJ), the lesions mainly included cell edema (denoted by arrowhead “←”)

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