Effects of silybin supplementation on nutrient digestibility, hematological parameters, liver function indices, and liver-specific mi-RNA concentration in dogs

Table 7 The urine cortisol/creatinine ratio of dogs fed diets supplemented with silybin and commercial hepatoprotectant (EXP1)

Item	Unit	CON (n = 18) mean	HEP (n = 18) mean	SIL (n = 18) mean	SEM	P
pH		7.56	6.88	7.00	0.21	NSD
Cortisol	μg/dl	13.5	13.7	13.4	0.11	NSD
Creatinine	μmol/l	16,419	14,431	12,907	1017	NSD
Cortisol: creatinine	10⁻⁶	29.4	26.5	28.2	0.85	NSD

Abbreviations: CON, control group; HEP, group fed diet supplemented with commercial hepatoprotectant containing silybin; SIL group fed diet supplemented with pure silybin; NSD, not statistically different

ISSN: 1746-6148