Skip to main content
Fig. 4 | BMC Veterinary Research

Fig. 4

From: Involvement of the VEGF signaling pathway in immunosuppression and hypoxia stress: analysis of mRNA expression in lymphocytes mediating panting in Jersey cattle under heat stress

Fig. 4

Heat-related DEG coexpression network and the expression of VEGF and PTGS2 in the VEGF pathway. a Coexpression network diagram of the 16 heat-related DEGs, with a positive relationship between PTGS2 and VEGF. b Diagram of the VEGF signaling pathway showing that VEGFA binds VEGFR2 at the membrane before triggering PLCy-CNLP-NFAT signaling to activate expression of the target gene COX2/PTGS2. c Verification of VEGF and PTGS2 expression. Scanned images of the protein levels of both VEGF and PTGS2 under different THIs (THI77, THI82, and THI88). c) Changes in relative mRNA expression determined using Q-PCR. d Changes in VEGF expression in lymphocte caused by different THIs (THI77, THI82, and THI88). d) Changes in relative mRNA expression determined using Q-PCR. e Changes in PTGS2 expression in lymphocytes caused by different THIs (THI77, THI82, and THI88). e) Changes in relative mRNA expression determined using Q-PCR

Back to article page