Table 1 Summary of mean values of food consumption and body weight changes for healthy Beagle dogs treated with enflicoxib orally once a week for up to 7 months (SD)
Treatment group | Weeks | 0X | 1X | 3X | 5X | ||
|---|---|---|---|---|---|---|---|
Dose (loading+maintenance) | (Placebo) | (8 + 4 mg/kg) | (24 + 12 mg/kg) | (40 + 20 mg/kg) | Pa | ||
Food consumption (g/animal/day) | Males | 1 to 13 | 298 (53) | 297 (47) | 271 (48) | 306 (36) | ns |
1 to 32 | 305 (51) | 309 (51) | 273 (46) | – | ns | ||
Females | 1 to 13 | 243 (52) | 222 (26) | 226 (34) | 244 (44) | ns | |
1 to 32 | 251 (52) | 240 (18) | 233 (30) | – | ns | ||
Body weight increase (Kg) | Males | 1 to 13 | 1,3 (0,3) | 1,1 (0,5) | 1,1 (0,2) | 1,5 (0,3) | ns |
1 to 32 | 1,8 (0,2) | 1,1 (0,2) | 1,7 (0,1) | – | ns | ||
Females | 1 to 13 | 0,5 (0,3) | 0,2 (0,5) | 0,6 (0,4) | 0,7 (0,7) | ns | |
1 to 32 | 1,4 (0,9) | 0,9 (0,6) | 1,0 (0,4) | – | ns | ||