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Table 1 Summary of mean values of food consumption and body weight changes for healthy Beagle dogs treated with enflicoxib orally once a week for up to 7 months (SD)

From: Long-term safety evaluation of Daxocox® tablets (enflicoxib) in dogs after weekly oral administrations for seven months

Treatment group   Weeks 0X 1X 3X 5X  
Dose (loading+maintenance)   (Placebo) (8 + 4 mg/kg) (24 + 12 mg/kg) (40 + 20 mg/kg) Pa
Food consumption (g/animal/day) Males 1 to 13 298 (53) 297 (47) 271 (48) 306 (36) ns
1 to 32 305 (51) 309 (51) 273 (46) ns
Females 1 to 13 243 (52) 222 (26) 226 (34) 244 (44) ns
1 to 32 251 (52) 240 (18) 233 (30) ns
Body weight increase (Kg) Males 1 to 13 1,3 (0,3) 1,1 (0,5) 1,1 (0,2) 1,5 (0,3) ns
1 to 32 1,8 (0,2) 1,1 (0,2) 1,7 (0,1) ns
Females 1 to 13 0,5 (0,3) 0,2 (0,5) 0,6 (0,4) 0,7 (0,7) ns
1 to 32 1,4 (0,9) 0,9 (0,6) 1,0 (0,4) ns
  1. aTreated groups compared with 0X group using Williams’ test (ns: p > 0.05, * p < 0.05, ** p < 0.01)
  2. N = 4 animals/sex/treatment group