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Table 5 Estimated doses for dairy cattle, steer and pig

From: Pharmacokinetics and pharmacodynamics of enrofloxacin treatment of Escherichia coli in a murine thigh infection modeling

Animal species Conversion
rate
fu Clearance F 1-log10 reduction
MIC90 = 0.25
3-log10 reduction
MIC90 = 0.25
Dairy cattle 59% 40.6% 34.8 L/day/kg 1 4.05 mg/kg 11.1 mg/kg
Steer 64% 39.2% 16.8 L/day/kg 1 1.42 mg/kg 6.78 mg/kg
Pig 10% 66% 4.43 L/day/kg 1 0.66 mg/kg 1.45 mg/kg
  1. The conversion rate is the ENR to CIP. fu is the free (unbound) fraction. F is the absolute bioavailability. MIC90 is the 90th percentile of MIC distribution