Table 1 CC50 values for vehicle (DMSO) and betulin
cell line | DMSO (MTT) | betulin | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MTT | NRU | SRB | ||||||||||
24 h | 48 h | 72 h | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h | |
NIH/3T3 | 2.989 ± 0.159 | 2.374 ± 0.395 | 1.635 ± 0.423 | 1.532 ± 0.005 | 1.585 ± 0.64 | 1.853 ± 0.647 | ˃15.625 | 7.329 ± 2.942 | 12.954 ± 2.942 | 10.87 ± 7.338 | 4.051 ± 1.242 | 3.756 ± 0.572 |
BF-2 | 5.031 ± 0.423 | 4.434 ± 0.717 | 4.794 ± 0.337 | 3.394 ± 0.903 | 2.751 ± 1.051 | 3.021 ± 1.034 | 27.615 ± 9.006 | 16.462 ± 3.599 | 14.516 ± 3.41 | >31.25 | >31.25 | >31.25 |