Genetic characterization of an H5N6 avian influenza virus with multiple origins from a chicken in southern China, October 2019

Table 1 Molecular characteristics of H5 isolates associated with pathogenicity

Virus	Subtype	Clade	Pathotype	HA			NA			PB2		PB1
				Cleavage site	RBS		stalk deletion	274	294	23	627	473
					186	226–228
A/Anhui/1/2005	H5N1	2.3.4	HPAI	RERRRKRGLF	N	QSG	YES	H	N	T	E	V
A/Hunan/1/2009	H5N1	2.3.4.1	HPAI	RERRRKRGLF	N	QSG	YES	H	N	T	E	V
A/goose/Yunnan/6193/2006	H5N1	2.3.4.2	HPAI	RERRRKRGLF	N	QSG	YES	H	N	T	E	V
A/avian/Hong_Kong/2372/2007	H5N1	2.3.4.3	HPAI	RERRRKRGLF	N	QSG	YES	H	N	T	E	V
A/duck/Hunan/2.06_YYGK78J3-OC/2018	H5N6	2.3.4.4	HPAI	RERRRKRGLF	N	QRG	NO	H	N	T	E	V
A/chicken/Dongguan/1101/2019	H5N6	2.3.4.4	HPAI	RERRRKRGLF	N	QRG	YES	H	N	T	E	V
A/muscovy duck/Japan/AQ-HE30-77C2/ 2018	H5N6	2.3.4.4	HPAI	RERRRKRGLF	N	QRG	YES	H	N	T	E	V

ISSN: 1746-6148