Fig. 6

Cytologic examination of an impression smear from a biopsy obtained from the left nares. The smears are of low cellularity with (a, b) few nucleated cells: variably degenerate neutrophils (**) and macrophages (***), with epithelial cells and occasional small lymphocytes (not shown) and (c) rare erythrocytes (^) in a lightly proteinaceous background with streaming mucoid material. Pale blue structures (approximately 2 × 4 μm) with a peripheral pink nuclear-type structure and a thin, clear capsule – consistent with Histoplasma capsulatum (yeast form) – are rarely seen extracellularly (arrows)