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Table 2 Inflammatory markers (Median, IQR) and NT–proBNP concentrations (Median, IQR) in patients and control dogs

From: Inflammation and its association with oxidative stress in dogs with heart failure

 

Control

(n = 10)

No CHF

(n = 11)

CHF

(n = 26)

TNF-α (pg/mL)

3.90; 3.90–10.50

3.90; 3.90–3.90

3.90; 6.85–11.90a

IL-6 (pg/mL)

31.3; 31.3–31.3

31.3; 31.3–31.3

31.3; 31.3–31.3

CRP (mg/L)

0.90; 0.78–1.33

1.45; 0.57–7.74

3.53; 1.10–13.18b

WBC (× 109/L)

6.2; 5.2–8.2

7.7; 6.3–8.9

10.5; 8.1–13.6c

NEUT (× 109/L)

3.4; 2.8–5.2

5.2; 3.2–6.8

7.2; 5.7–10.3b

Neutrophils (%)

57.3; 51.2–60.7d

66.3; 63.2–75.9

69.5; 61.3–73.5

LYMPH (× 109/L)

1.83; 1.47–2.35

1.28; 1.18–2.26

1.96; 1.57–2.89a

Lymphocytes (%)

30.7; 24.8–35.0d

17.4; 14.2–26.0

20.0; 14.7–24.6

MONO (× 109/L)

0.28; 0.21–0.39

0.42; 0.28–0.55

0.60; 0.44–0.84c

Monocytes (%)

4.2; 3.6–6.4

5.5; 4.5–6.2

5.7; 4.3–7.7

NT–proBNP (pmol/L)

822; 507–1201

1207; 927–3086

4773; 2828–8529c

  1. aSignificant difference (P < 0.05) when compared to patients without CHF; bSignificant difference (P < 0.05) when compared to control dogs; cSignificant difference (P < 0.05) when compared to control dogs and patients without CHF; dSignificant difference (P < 0.05) when compared to patients without and with CHF