Skip to main content
Fig. 3 | BMC Veterinary Research

Fig. 3

From: Investigation of synovial fluid lubricants and inflammatory cytokines in the horse: a comparison of recombinant equine interleukin 1 beta-induced synovitis and joint lavage models

Fig. 3

Lubricin and sulfated glycosaminoglycan (sGAG) concentrations in the synovial fluid of middle carpal joints (MCJ) and tarsocrural joints (TCJ) following IL-1β-induced synovitis or intra-articular lavage. Lubricin increased from baseline for 2 weeks following synovitis induction in both synovitis and contralateral MCJ (a). Lubricin increased from baseline for 72 h following lavage with the contralateral TCJ concentration being greater than synovitis TCJ at 72 and 168 h post-lavage (b). sGAG concentration increased from baseline for 72 h and was greater in synovitis MCJ as compared to contralateral MCJ during that time. sGAG concentration decreased from baseline at 3, 4 and 5 weeks post-induction of synovitis (c). sGAG concentration increased from baseline from 24 to 72 h following lavage and decreased from baseline 3 and 4 weeks with no differences from contralateral TCJ (d). An asterisk indicates a difference from baseline, and a triangle indicates a difference from the contralateral limb at the same time point. Graphed values are marginal means +/− SEM

Back to article page