Table 1 Summary of treatment and outcome
Case | Sex | ASO | ATO | ALRS | AET | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
1 | M | 75 | 78 | 104 | 896 | PHB | Epilepsy remission. Died at 3920 days. Postmortem: CRD |
2 | M | 71 | 73 | 107 | 610 | PHB | Epilepsy remission. Phenobarbital dose 0.44 mg/kg/SID since day 373. Died at 631 days. Postmortem: CRD. |
3 | M | 116 | 124 | 125 | 712 | PHB | Epilepsy remission. Died at 1409 days. Postmortem: CRD |
4 | M | 157 | – | – | 191 | – | Died at 192 days. Postmortem: Bacterial septicaemia (Salmonella spp) |
5 | M | 75 | 77 | 457 | Unfinished | PHB | ES remission. Phenobarbital dose 0.6 mg/kg/SID since day 1537. Current age 3543 days |
6 | M | 63 | 64 | 76 | Unfinished | PHB | Died at 134 days. Postmortem: Oesophageal foreign body. |
7 | F | 69 | 82 | 1599 | Unfinished | PHB, IMP | Died at 2526 days. Postmortem: Cardiac insufficiency. |
8 | F | 62 | 66 | 87 | 452 | PHB | Epilepsy remission. Current age 2845 days. |
9 | F | 77 | 78 | 77 | 482 | PHB | Epilepsy remission. Current age 2835 days. |
10 | F | 64 | 66 | 398 | Unfinished | PHB | Died at 428 days during cluster ES. Postmortem: Multiorgan failure and DIC associated with haemorrage and oedema affecting piriform and temporal lobes bilaterally. |
11 | F | 64 | 65 | 66 | 99 | PHB | Epilepsy remission. Current age 2101 days. |
12 | M | 795 | 796 | 857 | Unfinished | PHB, IMP | ES remission. Current age 2104 days. |
13 | M | 74 | 75 | 140 | Unfinished | PHB | ES remission. Phenobarbital dose 0.46 mg/kg/SID since day 522. Current age 1738 days. |
14 | M | 67 | 68 | 68 | 1648 | PHB | Epilepsy remission. Phenobarbital dose 0.42 mg/kg/SID since day 522. Current age 1738 days. |
15 | F | 63 | 72 | 827 | Unfinished | PHB, IMP | Euthanasia performed at 853 days due to a severe deterioration and poor quality of live. Postmortem: no significant findings. |
16 | F | 65 | 71 | 900 | Unfinished | PHB, IMP | ES remission. Current age 1753 days. |
17 | M | 66 | 70 | 317 | Unfinished | PHB | ES remission. Current age 1398 days. |
18 | M | 63 | 67 | 451 | Unfinished | PHB, IMP | Died at 451 days. Postmortem: Bacterial septicaemia (Streptococcus spp) |
19 | M | 60 | 80 | 79 | 361 | PHB, IMP | Epilepsy remission. Imepitoin started due to an early withdrawal of phenobarbital. Current age 956 days. |
20 | F | 73 | 75 | 1148 | Unfinished | PHB, LVT, PGB, ZNS | Euthanasia performed at 1157 days due to a severe deterioration and poor quality of live. Postmortem: no significant findings. |