Table 1 Outcome of infection with different doses of PRV-GD2013-ΔgI/gE and PRV-GD2013 in mice
Viruses | Groups | Amounts | Doses (TCID50) | Mortality (mean days to death) | LD50(TCID50) |
|---|---|---|---|---|---|
PRV-GD2013 | 1 | 5 | 106.0 | 5/5 (3.8) | 102.67 |
2 | 5 | 105.0 | 5/5 (4.0) | ||
3 | 5 | 104.0 | 5/5 (4.25) | ||
4 | 5 | 103.0 | 3/5 (5.0) | ||
5 | 5 | 102.0 | 1/5 (5.0) | ||
6 | 5 | 101.0 | 0/5 | ||
PRV-GD2013-ΔgI/gE | 7 | 5 | 106.0 | 5/5 (5.0) | 104.33 |
8 | 5 | 105.0 | 5/5 (5.8) | ||
9 | 5 | 104.0 | 2/5 (6.0) | ||
10 | 5 | 103.0 | 1/5 (6.0) | ||
11 | 5 | 102.0 | 0/5 | ||
12 | 5 | 101.0 | 0/5 | ||
DMEM | 13 | 5 | 0.1 ml | 0/5 | / |