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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Recombinant pseudorabies virus with gI/gE deletion generated by overlapping polymerase chain reaction and homologous recombination technology induces protection against the PRV variant PRV-GD2013

Fig. 5

a Pathological examination of organ tissues. Groups of piglets (n = 3) were inoculated with 105 TCID50 PRV-GD2013, 105 TCID50 PRV-GD2013-ΔgI/gE, or DMEM. At 17 dpi, all surviving piglets were euthanized and necropsied. Tissue samples from the brain, lymph nodes, lung, kidney, liver, spleen were collected and used for pathological examination. b Pathological changes in various organ tissues of immunized piglets that were challenged with PRV-GD2013. Groups of piglets (n = 5) were inoculated with 105 TCID50 PRV-GD2013-ΔgI/gE, 104 TCID50 PRV-GD2013-ΔgI/gE, 103 TCID50 PRV-GD2013-ΔgI/gE, Bartha-K61, or DMEM. At 14 dpc, all surviving piglets were euthanized and necropsied. Tissue samples from the brain, lymph nodes, lung, kidney, liver, spleen were collected and used for pathological examination

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