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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Streptozotocin induces alpha-2u globulin nephropathy in male rats during diabetic kidney disease

Fig. 2

Histopathological changes in the kidneys of STZ-induced hyperglycaemic rats during diabetic kidney disease. a-g: Renal histopathological appearance by H&E staining; a: intact kidney from non-alpha 2u-globulin nephropathic rats with preserved PCTs (*), DCTs (d) and glomerulus (arrow); b-g: pathological changes in alpha 2u-globulin nephropathic rats consisting of Bowman’s space distension (b; arrow) with proteinaceous fluid deposition (b; #), PCT degeneration and hyaline cast deposition (b; *, c; *, d; arrow and e; *), intracytoplasmic hyaline droplet deposition in PCTs (c; arrow and d), vacuolated degeneration in the PCT (d; arrow) with sloughed epithelial cells (e; arrow) and tubular degeneration (f; #) and regeneration with flattening and basophilia (g; arrow)

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