Fig. 4From: First-line management of canine status epilepticus at home and in hospital-opportunities and limitations of the various administration routes of benzodiazepinesSchematic illustration of the indirect and direct (nose-brain) nasal drug delivery pathways. Drugs administered IN can penetrate directly into the brain through the olfactory and/or trigeminal nerve pathways or indirectly following absorption into the systemic blood circulation. Figures from authors’ personal record modified with microsoft power pointBack to article page