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Table 1 Comparison of cell densities between Cell Factory and CelCradle™ -500A culture systems

From: Production of small ruminant morbillivirus, rift valley fever virus and lumpy skin disease virus in CelCradle™ -500A bioreactors

  Vero cells LT cells
  CelCradle™-500A Cell Factory CelCradle™-500A Cell Factory
Inoculum (cell/ cm2) 10,000 40,000 15,000 40,000
Harvest (cell/ cm2) 192,000 150,000 43,000 98,000
Incubation time (days) 5 4 8 6
Fold-increase in cell numbers × 19 × 3.7 × 3 × 2.5
Cell doubling time (h) 28 h 24 h 86 h 76 h
Medium volume (ml/cm2) 32 ml 237 ml 32 ml 237 ml