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Table 4 Numbers of differentially expressed genes for the factors of Isolate, TVclass, and WUR genotype based on the NanoString data with or without accounting for cell enrichments

From: Gene expression in tonsils in swine following infection with porcine reproductive and respiratory syndrome virus

Factor and contrast

Without cell enrichment

With cell enrichment

Overlap of differentially expressed genes

log2FC < 0a

log2FC > 0b

log2FC < 0a

log2FC > 0b

Isolate: KS06 vs NVSL

17

74

9

35

26

TVclass: High vs Low

16

36

13

28

9

WUR: AB vs AA

0

0

21

14

0

 (HighAB-HighAA) vs (LowAB-LowAA)

-c

-c

6

36

-c

 (KS06AB-KS06AA) vs (NVSLAB-NVSLAA)

-c

-c

64

20

-c

  1. a Gene expression of KS06 > NVSL, or Low>High, or AB>AA, or (HighAB-HighAA) > (LowAB-LowAA), or (KS06AB-KS06AA) > (NVSLAB-NVSLAA)
  2. b Gene expression of KS06 < NVSL, or Low<High, or AB<AA, or (HighAB-High_AA) < (LowAB-LowAA), or (KS06AB-KS06AA) < (NVSLAB-NVSLAA)
  3. c This factor was not included in the model