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Table 1 Repeatability and reliability for fasting indices obtained from insulin and glucose concentrations measured on two consecutive days in 60 horses

From: Evaluation of fasting plasma insulin and proxy measurements to assess insulin sensitivity in horses

Variable

Day 1 Median (IQR)

Day 2 Median (IQR)

CV% (CI)

ICC

CR%

Paired t-test (between-test days) P value

Insulin sensitivity:

 1/insulin (mL/µIU)

0.088 (0.032–0.22)

0.076 (0.032–0.17)

23.8 (19.2–27.7)

0.95

65

0.10

 RISQI ([µIU/mL]−0.5)

0.30 (0.18–0.47)

0.28 (0.18–0.41)

12.2 (9.7–14.2)

0.95

33

0.14

 QUICKI

0.33 (0.28–0.39)

0.32 (0.28–0.37)

3.9 (2.9–4.6)

0.94

10

0.06

β-cell response:

 FI (µIU/mL)

11.4 (4.7–31.9)

13.2 (6.0–31.5)

23.8 (19.2–27.7)

0.95

65

0.11

 MIRG ([µIU]2 /[10\(\times\)mL\(\times\)mg)

4.9 (3.1–8.5)

13.2 (6.0–8.8)

17.5 (13.0–21.1)

0.89

47

0.03

 HOMA-β

126 (75–306)

125 (81–257)

25.3 (21.3–28.7)

0.91

70

0.26

  1. RISQI reciprocal of the square root of insulin; QUICKI quantitative insulin sensitivity check index; FI fasting insulin concentration; MIRG modified insulin-to-glucose ration; HOMA-β homeostatic model assessment of β-cell function; IQR interquartile range; CV coefficient of variation; ICC intraclass correlation coefficient; CR coefficient of repeatability