Fig. 3
Heatmap illustrating one biogenic amine and three glycerophospholipids that showed a significant association with subsequent laminitis in samples collected from ponies before and after feeding. Kynurenine concentrations were low in basal samples and increased postprandially in non-laminitic (NL) ponies, but showed the opposite pattern in ponies that subsequently developed laminitis (PL). Log FC is the log2 fold change of the difference of differences between basal and postprandial samples from both PL and NL groups. The features are grouped by functional classes. Two features decrease in PL while increasing in NL postprandially (kynurenine and PC aa C30:2), while the other two (positive logFC) show an opposite pattern