TY - JOUR AU - Michałek, Marcin AU - Tabiś, Aleksandra AU - Pasławska, Urszula AU - Noszczyk-Nowak, Agnieszka PY - 2020 DA - 2020/01/30 TI - Antioxidant defence and oxidative stress markers in cats with asymptomatic and symptomatic hypertrophic cardiomyopathy: a pilot study JO - BMC Veterinary Research SP - 26 VL - 16 IS - 1 AB - Hypertrophic cardiomyopathy is the most common cardiovascular cause of death in cats. Although the majority of cats remain asymptomatic, some may develop signs of chronic heart failure due to diastolic failure, arterial thromboembolism (ATE) or sudden cardiac death. Therefore, it is crucial to identify individuals that are in high risk of developing cardiac complications before the onset of life-threatening signs. Oxidative stress is the imbalance between the production and neutralisation of reactive oxygen species. Uncontrolled reactive oxygen species overproduction leads to protein and lipid peroxidation and damages the DNA strands, injuring the cells and leading to their death. The aim of the study was to evaluate the oxidative state in cats with hypertrophic cardiomyopathy and healthy controls. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-020-2256-3 DO - 10.1186/s12917-020-2256-3 ID - Michałek2020 ER -