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Table 5 Gene expression profiling of liver samples by qPCR

From: Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.)

Gen category and function

Gen symbol

Fold changea

P-valueb

Lipid uptake and transport

 Fatty acid transporter

cd36

0.948

0.711

 Fatty acid transporter

fatp

0.992

0.923

 Lipoprotein component

apo(B100)liver

0.996

0.983

 Lipid droplet component

plin2

1.626

0.013

 Nuclear receptor – regular of lipid metabolism

pparα

0.660

0.182

 Nuclear receptor – regular of lipid metabolism

pparγ

0.973

0.834

Phosphatidylcholine synthesis

 Phosphatidylcholine biosynthesis

pemt

0.998

0.988

 Phosphatidylcholine biosynthesis

chk

0.505

0.116

 Phosphatidylcholine biosynthesis

pcyt1a

0.923

0.597

Cholesterol metabolism

abc1a1

0.851

0.310

 Bile acid nuclear receptor

fxr

1.154

0.265

 Cholesterol biosynthesis

hmgcr

0.936

0.479

 Cholesterol biosynthesis

cyp7a1

0.925

0.580

 Cholesterol efflux transporter

abca1

0.855

0.289

 Cholesterol efflux transporter

   

 Cholesterol efflux transporter

abcg5

1.063

0.601

 Cholesterol transporter

npc1l1

0.955

0.776

 Nuclear receptor - regular of lipid and sterol metabolism

lxr

0.837

0.156

 Nuclear receptor - regular of lipid and sterol metabolism

srebp1

0.944

0.851

 Nuclear receptor - regular of lipid and sterol metabolism

srebp2

1.174

0.405

ROS metabolism / antioxidant

 Superoxide dismutation

sod3

0.739

0.374

Nuclear receptor – control of gene transcription

 Transcription factor

rxr

0.789

0.104

Mannose metabolism

 Glycosylation

pmm

0.759

0.029

  1. aValues are mean fold change observed in the choline diet fed group in comparison with those in the control group
  2. bP-values in bold indicate significant differences between the two treatments; italicized values represent trends