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Table 4 Gene expression profiling of pyloric caeca samples by qPCR

From: Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.)

Gen category and function

Gen symbol

Fold changea

P-valueb

Lipid uptake and transport

 Fatty acid transporter

cd36

1.13

0.175

 Fatty acid transporter

fabp2b

1.37

0.004

 Fatty acid transporter

fabp2a1

1.11

0.302

 Fatty acid transporter

fabp2a2

1.01

0.962

 Fatty acid transporter

fatp

0.89

0.120

 Lipoprotein assembly

mtp

1.12

0.259

 Lipoprotein component

apoB48

1.07

0.730

 Lipoprotein component

apoAIV

1.58

0.028

 Lipoprotein component

apoAI

1.42

0.001

 Lipid droplet component

plin2

0.273

< 0.001

 Nuclear receptor – regular of lipid metabolism

pparα

1.52

0.037

 Nuclear receptor – regular of lipid metabolism

pparγ

1.38

0.024

 Resynthesis of triacylglycerols

mgat2a

1.39

0.023

Phosphatidylcholine synthesis

 Choline transporter

slc44a2

1.09

0.329

 Phosphatidylcholine biosynthesis

pemt

0.95

0.486

 Phosphatidylcholine biosynthesis

chk

0.61

0.068

 Phosphatidylcholine biosynthesis

pcyt1a

0.58

0.004

Cholesterol metabolism

 Bile acid nuclear receptor

fxr

1.15

0.415

 Cholesterol biosynthesis

hmgcr

0.91

0.260

 Cholesterol efflux transporter

abca1

0.95

0.650

 Cholesterol efflux transporter

abcg5

1.61

0.004

 Cholesterol esterification

acat

0.95

0.677

 Cholesterol transporter

npc1l1

1.58

< 0.001

 Nuclear receptor - regular of lipid and sterol metabolism

lxr

1.06

0.580

 Nuclear receptor - regular of lipid and sterol metabolism

srebp1

0.55

0.159

 Nuclear receptor - regular of lipid and sterol metabolism

srebp2

1.04

0.907

 Taurine transporter - bile salt metabolism

slc6a6

1.39

0.001

  1. aValues are mean fold change observed in the choline diet fed group in comparison with those in the control group
  2. bP-values in bold indicate significant differences between the two treatments; italicized values represent trends