Fig. 5
From: N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice
Effect of NAC on oxidative stress markers alteration in L. amazonensis infected animals. As show in Fig. 5A in infected + vehicle mice we observed a significant depletion of GSH levels, that have been restored by NAC treatment. The result in Fig. 5B, showed that the level of MDA was decreased significantly in tissue collected from mice treated with NAC compared to L. amazonensis + vehicle infected animals. Furthermore, we observed that the activities of SOD Fig.5C, were significantly increased in tissue taken from NAC group treated compared to infected + vehicle mice group. Values are means ± SEM of five animals for each group. ##P < 0.01,###P < 0.001 vs. L. amazonensis infected mice; ***P < 0.001 vs. sham