Skip to main content
Fig. 1 | BMC Veterinary Research

Fig. 1

From: N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice

Fig. 1

Effect of oral NAC on L. amazonensis infected mice on paw edema histological damage and neutrophil infiltration in paw skin. Paw edema (A) was assessed at the time points indicated after subcutaneous injection of L. amazonensis into the mice hind paw. NAC administration (200 mg/kg) produced significant improvements in this scores. Histological analysis was achieved by hematoxylin/eosin staining in sham; (B), L. amazonensis subcutaneously infected mice into the hind paw (C), and L. amazonensis subcutaneously infected mice + NAC (200 mg/kg) (D); moreover myeloperoxidase (MPO) activity in paw skin was evaluated (E). Figures are representative of at least three independent experiments for all animals from each group. Values are means ± SEM of five animals for each group. ###P < 0.001 vs. L. amazonensis infected mice; ***P < 0.001 vs. sham

Back to article page
\