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Table 4 Detection of VSV neutralizing antibodies in goats induced by recombinant adenovirus with VSV-NJ at different time points

From: Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

Group Mean titers over time after first immunizationa  
0 weeks 3 weeks 6 weeks 9 weeks 12 weeks
rAd-IN 0 5 (4–8) 10 (8–16) 10 (8–16) 12 (8–16)
rAd-NJ 0 6 (4–8) 20 (16–20) 47 (32–64) 20 (16–32)
rAd-IN-NJ 0 6 (4–8) 18 (8–18) 47 (32–64) 24 (16–24)
wtAd 0 0 0 0 0
PBS 0 0 0 0 0
  1. aMean neutralizing antibody titers at that time point (range of antibody titers). VSV-NJ vesicular stomatitis virus-New Jersey; rAd-IN recombinant adenovirus-Indiana; rAd-NJ recombinant adenovirus-New Jersey; rAd-IN-NJ recombinant adenovirus-Indiana-New Jersey; wtAd wild-type adenovirus; PBS, phosphate-buffered saline