Skip to main content

Table 3 Detection of VSV neutralizing antibodies in mice induced by recombinant adenovirus with VSV-NJ at different time points

From: Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

Group Mean titers over time after first immunizationa
0 weeks 2 weeks 4 weeks 6 weeks
rAd-IN 0 < 2 (0–2) 6 (4–8) 8 (8)
rAd-NJ 0 < 2 (0–2) 10.4 (8–16) 24 (16–32)
rAd-IN-NJ 0 < 2 (0–2) 12 (8–16) 27.2 (16–32)
wtAd 0 0 6 (4–8) 8 (8)
PBS 0 0 10.4 (8–16) 24 (16–32)
  1. aMean neutralizing antibody titers at that time point (range of antibody titers). VSV-NJ vesicular stomatitis virus-New Jersey; rAd-IN recombinant adenovirus-Indiana; rAd-NJ recombinant adenovirus-New Jersey; rAd-IN-NJ recombinant adenovirus-Indiana-New Jersey; wtAd wild-type adenovirus; PBS phosphate-buffered saline