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Table 1 Detection of VSV neutralizing antibodies in mice induced by recombinant adenovirus with VSV-IN at different time points

From: Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

Group

Mean titers over time after first immunizationa

0 weeks

2 weeks

4 weeks

6 weeks

rAd-IN

0

< 2 (0–2)

10.4 (8–16)

24 (16–32)

rAd-NJ

0

< 2 (0–2)

6 (4–8)

10.4 (8–16)

rAd-IN-NJ

0

< 2 (0–2)

24 (16–32)

28.8 (16–32)

wtAd

0

0

0

0

PBS

0

0

0

0

  1. aMean neutralizing antibody titers at that time point (range of antibody titers). VSV-IN vesicular stomatitis virus-Indiana; rAd-IN recombinant adenovirus-Indiana; rAd-NJ recombinant adenovirus-New Jersey; rAd-IN-NJ recombinant adenovirus-Indiana-New Jersey; wtAd wild-type adenovirus; PBS phosphate-buffered saline