Group | Mean titers over time after first immunizationa |
---|
0 weeks | 2 weeks | 4 weeks | 6 weeks |
---|
rAd-IN | 0 | < 2 (0–2) | 10.4 (8–16) | 24 (16–32) |
rAd-NJ | 0 | < 2 (0–2) | 6 (4–8) | 10.4 (8–16) |
rAd-IN-NJ | 0 | < 2 (0–2) | 24 (16–32) | 28.8 (16–32) |
wtAd | 0 | 0 | 0 | 0 |
PBS | 0 | 0 | 0 | 0 |
- aMean neutralizing antibody titers at that time point (range of antibody titers). VSV-IN vesicular stomatitis virus-Indiana; rAd-IN recombinant adenovirus-Indiana; rAd-NJ recombinant adenovirus-New Jersey; rAd-IN-NJ recombinant adenovirus-Indiana-New Jersey; wtAd wild-type adenovirus; PBS phosphate-buffered saline