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Table 2 Mean ± SD heart rate and respiratory rate in both groups at different time points

From: Plasma levels of a methadone constant rate infusion and their corresponding effects on thermal and mechanical nociceptive thresholds in dogs

Time (h)

Heart rate (beats min−1)

Respiratory rate (breath min− 1)

Group M

Group P

Group M

Group P

BL

87 ± 12

82 ± 11

16 ± 3

19 ± 4

0.75

66 ± 17*

83 ± 9

12 ± 2*

15 ± 5*

1.75

59 ± 13*

82 ± 14

12 ± 2*

14 ± 3*

2.75

63 ± 13*° (p = 0.0007)

94 ± 8*

13 ± 2*

18 ± 3

3.75

65 ± 11*

89 ± 6

13 ± 2*

14 ± 5*

5.75

61 ± 10*

79 ± 15

13 ± 2*

14 ± 5*

7.75

59 ± 13*

84 ± 7

12 ± 1*

14 ± 4*

9.75

59 ± 10*

82 ± 12

14 ± 2

14 ± 6*

11.75

57 ± 7*° (p = 0.0027)

86 ±10

13 ± 2*

13 ± 3*

23.75

66 ± 18*° (p = 0.0127)

93 ± 7*

14 ± 2

17 ± 3

25.75

55 ± 13*° (p = 0.0002)

88 ± 16

12 ± 0*

13 ± 2*

27.75

61 ± 14*

85 ± 14

15 ± 4

13 ± 2*

29.75

57 ± 12*° (p = 0.0072)

85 ± 16

11 ± 2*

14 ± 3*

31.75

59 ± 12*° (p = 0.0014)

89 ± 10

12 ± 0*

13 ± 3*

33.75

62 ± 14*

85 ± 10

11 ± 1*

12 ± 1*

35.75

60 ± 12*° (p = 0.0011)

90 ± 9

12 ± 0*

15 ± 3*

47.75

65 ± 16*° (p = 0.0182)

91 ± 9

13 ± 2*

16 ± 2

49.75

63 ± 18*

85 ± 10

12 ± 0*

14 ± 2*

51.75

63 ± 13*

83 ± 12

11 ± 1*

15 ± 4*

53.75

62 ± 14*° (p = 0.0260)

88 ± 7

12 ± 2*

13 ± 3*

55.75

55 ± 5*° (p = 0.0182)

82 ± 17

12 ± 0*

13 ± 2*

57.75

63 ± 14*

85 ± 12

12 ± 0*

13 ±2*

59.75

63 ± 11*° (p = 0.0018)

93 ± 8

13 ± 2*

14 ± 2*

71.75

69 ± 16*

87 ± 18

14 ± 3

14 ± 3*

73.75

71 ± 17*

86 ± 14

13 ± 2*

14 ± 2*

75.75

75 ± 28*

87 ± 16

13 ± 2*

13 ± 2*

77.75

80 ± 28

82 ± 18

15 ± 4

12 ± 3*

79.75

95 ± 27

88 ± 12

14 ± 4

13 ± 2*

81.75

90 ± 16

78 ± 15

14 ± 2

13 ± 2*

83.75

103 ± 13*

93 ± 16*

15 ± 3

14 ± 2*

95.75

103 ± 14*

89 ± 9

17 ± 5

17 ± 3

  1. BL Baseline
  2. *significant difference (p < 0.05) to baseline in M
  3. ° significant difference (p < 0.05) between groups, displayed p values refer to significant differences between groups
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BMC Veterinary Research

ISSN: 1746-6148

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