Skip to main content

Table 1 Pharmacokinetic data of methadone CRI in mean ± SD

From: Plasma levels of a methadone constant rate infusion and their corresponding effects on thermal and mechanical nociceptive thresholds in dogs

  Mean SD
Total body clearance (ml kg− 1 min− 1) 51.44 9.47
Mean residence time (h) 3.40 1.74
Volume of distribution at steady state (l kg− 1) 10.26 5.53
Terminal half-life (h) 2.36 1.20