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Table 2 Effective concentrations of anthelmintics inhibiting 50% (EC50) and 99% (EC99) of larvae in gastrointestinal nematode (GIN) populations from herds classified as susceptible and resistant, presented as the median, interquartile range (IQR), and range in parenthesis

From: Prevalence of anthelmintic resistance of gastrointestinal nematodes in Polish goat herds assessed by the larval development test

GIN population No. of herds EC50 EC99
Benzimidazoles – discriminating concentration (DC) = 0.08 μg/ml
 susceptible 5 0.003, 0.003–0.007 (0.001–0.009) 0.011, 0.008–0.014 (0.001–0.042)
 resistant 37 0.150, 0.050–0.301 (0.014–1.649) 2.990, 0.872–7.371 (0.135–974.682)
Macrocyclic lactones – DC = 21.6 ng/ml
 susceptible 2 0.892 (0.135–1.649) 14.902 (13.398–16.400)
 resistant 40 49.402, 24.533–77.576 (3.669–148.413) 1092.628, 396.322–3122.438 (47.127–257,437.7)
Levamisole – DC = 2.0 μg/ml
 susceptible 37 0.202, 0.135–0.301 (0.025–0.549) 0.724, 0.480–1.148 (0.062–2.185a)
 resistant 5 0.497, 0.449–0.741 (0.301–2.718) 6.446, 3.121–231.343 (2.824–269.110)
  1. a GIN populations from two herds (no. 5 and 23 in Table 1) were classified as susceptible despite ED99 > 2 μg/ml because the corrected percentage larval development at the DC was ≤1%