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Table 5 Multiple regression final models for UAldo:C dependent variables in total population, Healthy + Stage B1 group and stage C group

From: Factors affecting the urinary aldosterone-to-creatinine ratio in healthy dogs and dogs with naturally occurring myxomatous mitral valve disease

 

Goodness of fit

Variables in the model

 

R squared

 

Coefficient

Significance

Total population (a)

0.263

(constant)

−0.148

0.881

LA/Ao

1.204

0.013*

Sex (female vs male)

1.838

0.003*

Chihuahua (YES vs NO)

3.615

< 0.001*

Healthy + Stage B1 (b)

0.444

(constant)

−2.537

0.101

Sex (female vs male)

1.958

0,014*

UP/UC

4.903

0,052

Chihuahua (YES vs NO)

4.323

< 0.001*

UREA mg/dL

0.089

0.018*

Stage C

(c)

0.145

(constant)

2.395

0.003

Furosemide dose (mg/kg/day)

0.336

0.024

  1. LA/Ao: left atrium-to-aortic root ratio; sex: female = 1, male = 0; Chihuahua: YES = 1, NO = 0; UP/UC Urinary protein-to-creatinine ratio, UREA Serum urea
  2. (a) Backward method step 0 predictors: body weight (kg), age (years), sex (female = 1 vs male = 0), Chihuahua (YES = 1 vs NO = 0), UREA mg/dL, UP/UC, LA/Ao, LVEDDn, E peak velocity m/s, spironolactone (YES = 1 vs NO = 0), pimobendan (YES = 1 vs NO = 0), furosemide (YES = 1 vs NO = 0), ACEI (YES = 1 vs NO = 0)
  3. (b) Backward method step 0 predictors: body weight (kg), age (years), sex (female = 1 vs male = 0), Chihuahua (YES = 1 vs NO = 0), UREA mg/dL, UP/UC, LA/Ao, LVEDDn, E peak velocity m/s, STAGE (Healthy = 0, stage B1 = 1)
  4. (c) Backward method step 0 predictors: body weight (kg), age (years), sex (female = 1 vs male = 0), Chihuahua (YES = 1 vs NO = 0), UREA mg/dL, UP/UC, LA/Ao, LVEDDn, E peak velocity m/s, spironolactone (YES = 1 vs NO = 0), furosemide dose (mg/kg/day), furosemide duration (days), ACEI dose (mg/kg/day), ACEI duration (days)
  5. * = significant (P value < 0.05)