Table 2 Comparison of antimicrobial therapy between 2016 and 2018
Total | University hospital | Private practices | ||||
|---|---|---|---|---|---|---|
2016 | 2018 | 2016 | 2018 | 2016 | 2018 | |
Pneumonia | n = 294 | n = 294 | n = 70 | n = 70 | n = 224 | n = 224 |
% [CIa] | % [CIa] | % [CIa] | % [CIa] | % [CIa] | % [CIa] | |
First line antimicrobial | 15.3 [11.6–19.9] | 26.5 [21.8–31.9] | 38.6 [28.0–50.3] | 62.9 [51.1–73.2] | 8.0 [5.1–12.3] | 15.2 [11.1–20.5] |
Second line antimicrobial | 25.2 [20.6–30.4] | 30.3 [25.3–35.8] | 15.7 [9.0–26.0] | 22.9 [14.6–34.0] | 28.1 [22.6–34.3] | 32.6 [26.8–39.0] |
Third line antimicrobial | 43.5 [38.0–49.3] | 27.9 [23.1–33.3] | 30.0 [20.5–41.5] | 7.1 [3.1–15.7] | 47.8 [41.3–54.3] | 34.4 [28.5–40.8] |
Unlisted antimicrobialb | 14.3 [10.7–18.7] | 13.6 [10.2–18.0] | 12.9 [6.9–22.7] | 2.9 [0.8–9.8] | 14.7 [10.7–20.0] | 17.0 [12.6–22.4] |
Non-antibiotic therapy | 1.7 [0.7–3.9] | 1.7 [0.7–3.9] | 2.9 [0.8–9.8] | 4.3 [1.5–11.9] | 1.3 [0.5–3.9] | 0.9 [0.2–3.2] |
Combination therapy | 4.1 [2.1–7.0] | 6.1 [3.7–9.5] | 1.4 [0.0–7.7] | 0.0 [0.0–5.1] | 4.9 [2.5–8.6] | 8.0 [4.8–12.4] |
Diarrhea | n = 296 | n = 296 | n = 72 | n = 72 | n = 224 | n = 224 |
% [CIa] | % [CIa] | % [CIa] | % [CIa] | % [CIa] | % [CIa] | |
First line antimicrobial | 8.1 [5.5–11.8] | 13.5 [10.1–17.9] | 22.2 [14.2–33.1] | 40.3 [29.7–51.8] | 3.6 [1.8–6.9] | 4.9 [2.8–8.6] |
Second line antimicrobial | 15.2 [11.6–19.7] | 14.5 [11.0–19.0] | 1.4 [0.2–7.5] | 20.8 [13.1–31.6] | 19.6 [15.0–25.3] | 12.5 [8.8–17.5] |
Third line antimicrobial | 3.7 [2.1–6.5] | 2.0 [0.9–4.4] | 11.1 [5.7–20.4] | 4.2 [1.4–11.5] | 1.3 [0.5–3.9] | 1.3 [0.5–3.9] |
Unlisted antimicrobialb | 49.7 [44.0–55.3] | 46.3 [40.7–52.0] | 48.6 [37.4–59.9] | 20.8 [13.1–31.6] | 50.0 [43.5–56.5] | 54.5 [47.9–60.9] |
Non-antibiotic therapy | 23.3 [18.9–28.5] | 23.6 [19.2–28.8] | 16.7 [9.8–26.9] | 13.9 [7.7–23.7] | 25.4 [20.2–31.5] | 26.8 [21.4–32.9] |
Combination therapy | 4.4 [2.4–7.4] | 8.4 [5.5–12.2] | 6.9 [2.3–15.5] | 1.4 [0.0–7.5] | 3.6 [1.6–6.9] | 10.7 [7.0–15.5] |
Otitis | n = 35 | n = 65 | ||||
% [CIa] | % [CIa] | |||||
First line antimicrobial | 31.4 [18.6–48.0] | 21.5 [13.3–33.0] | ||||
Second line antimicrobial | 8.6 [3.0–22.4] | 7.7 [3.3–16.8] | ||||
Third line antimicrobial | 42.9 [28.0–59.1] | 50.8 [38.9–62.5] | ||||
Unlisted antimicrobialb | 17.1 [8.1–32.7] | 18.5 [10.9–29.6] | ||||
Non-antibiotic therapy | 0.0 [0.0–9.9] | 1.5 [0.3–8.2] | ||||
Combination therapy | 11.4 [3.2–26.7] | 10.8 [4.4–20.9] | ||||