Table 2 iPSC characterization (specific to articles that investigated chimerism)
From: The use of induced pluripotent stem cells in domestic animals: a narrative review
Origin cell type | Suggested pluripotent state | iPSC characterization criteria | Reference | ||||
|---|---|---|---|---|---|---|---|
Pluripotency markers | Embryoid bodies | Teratomas | Chimeras | Germline transmission | |||
Porcine | |||||||
 Adult MSCs | Primed | Yes | Yes | Not tested | Yes | Yes | |
 Fetal fibroblasts | Naïve | Yes | Yes | Yes | Yes; limited to blastocyst | Not tested | [117] |
 Fetal fibroblasts | Naïve | Yes | Yes | No | Yes, limited to fetus | Not tested | [40] |
Ovine | |||||||
 Fetal fibroblasts | Primed | Yes | Yes | Yes | Yes; but low contribution at birth | Not tested | [108] |
Galline | |||||||
 Fetal fibroblasts | Primed | Yes | Yes | Not tested | Yes | Not tested | [20] |