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Table 1 Selected clinical, hematological and echocardiographic variables in healthy dogs and dogs with acute congestive health failure (CHF) (Mean ± Sd)

From: Platelet proteome changes in dogs with congestive heart failure

Parameter

Healthy Dogs

n = 10

Dogs with acute CHF

n = 10

P value

Clinical findings

 BW Kg

25.2 ± 6.5

22.4 ± 19.4

NS

 Age years

5.3 ± 1.1

8.1 ± 5.1

NS

 P bpm

111 ± 8

146 ± 28

< 0.001

 R breath/min

27 ± 7

68 ± 21

< 0.001

 VHS

9.3 ± 1.2

12.5 ± 1.5

< 0.001

Hematological and serum biochemistry findings

 Platelet ×103/μL

346 ± 66

325 ± 158

NS

 cTnI ng/mL

0.04 ± 0.02

0.15 ± 0.1

< 0.05

Echocardiographic findings

 IVSDd cm

1.1 ± 0.4

0.7 ± 0.1

NS

 LVDd cm

3.0 ± 0.7

5.0 ± 0.4

< 0.01

 LVPWDd cm

1.2 ± 0.2

1.3 ± 0.4

NS

 IVSSd cm

1.1 ± 0.3

1.1 ± 0.1

NS

 LVSd cm

2.1 ± 0.5

3.2 ± 0.3

< 0.01

 LVPWSd cm

1.1 ± 0.1

1.2 ± 0.3

NS

 FS %

34.4 ± 3.8

26.0 ± 6.4

< 0.05

 EF %

61.6 ± 9.2

48.0 ± 9.7

< 0.05

 EPSS cm

0.3 ± 0.1

0.8 ± 0.1

< 0.001

 LA/Ao

0.9 ± 0.2

2.6 ± 0.9

< 0.001

 PV/PA

0.9 ± 0.3

2.6 ± 0.4

< 0.001

 LVIDDn

1.16 ± 0.1

2.01 ± 0.2

< 0.01

 MV E/A

1.5 ± 0.3

3.8 ± 1.5

< 0.05

  1. BW body weight, P pulsation, R respiration, VHS vertebral heart score, cTnI cardiac troponin I, IVSDd interventricular septum diastole diameter, IVSSd interventricular septum systole diameter, LVDd left ventricular diastole diameter, LVSd left ventricular systole diameter, LVPWDd left ventricular post wall diastole diameter, LVPWSd left ventricular post wall systole diameter, FS fractional shortening, EF ejection fraction, EPSS E point to septal separation, LA/Ao left atrium to aortic ratio, PV/PA pulmonary vein to pulmonary artery ratio, LVIDDn normalized left ventricular internal dimension in diastole, MV E/A mitral valve early ventricular (E) and late atrial contraction (A), NS statistically not significant