Fig. 6
From: Multi-targeted gene silencing strategies inhibit replication of Canine morbillivirus
Ad5Ni(1–3) post-treatment at various time intervals. Multi-shRNA Ad5 construct was added at MOI of 2.5 and 5 to infected cells at 2, 12 and 24 hpi. Ad5 silencing efficiency was measured by viral RNA levels (a), infectious titers (b), and CDV plaque count (c) at time-specific treatments (** p < 0.01; *** p < 0.001). CDV infectivity inhibition was shown through reduction of CPE (D, 100X total magnification) and infectious plaque number (e) compared to controls