Table 4 Urinalysis of dogs on day 0, 45, 90 and 118
From: Beagle dog 90-day oral toxicity study of a novel coccidiostat – ethanamizuril
male | female | |||||
|---|---|---|---|---|---|---|
SG | pH | URO | SG | pH | URO | |
Day 0 | ||||||
High (n = 6) | 1.08 ± 0.03 | 7.60 ± 0.32 | 3.11 ± 0.13 | 1.04 ± 0.04 | 7.44 ± 0.51 | 3.15 ± 0.08 |
Middle (n = 4) | 1.09 ± 0.08 | 7.74 ± 0.56 | 3.07 ± 0.08 | 1.09 ± 0.15 | 7.39 ± 0.31 | 3.10 ± 0.09 |
Low(n = 4) | 1.11 ± 0.04 | 7.49 ± 0.45 | 3.09 ± 0.06 | 1.09 ± 0.04 | 7.33 ± 0. 42 | 3.17 ± 0. 06 |
Control(n = 6) | 1.05 ± 0.02 | 7.29 ± 0.27 | 3.09 ± 0.07 | 1.13 ± 0.08 | 7.49 ± 0.27 | 3.17 ± 0.06 |
Day 45 | ||||||
High (n = 6) | 1.07 ± 0.05 | 7.32 ± 0.33 | 3.11 ± 0.13 | 1.11 ± 0.11 | 7.41 ± 0.53 | 3.15 ± 0.08 |
Middle (n = 4) | 1.09 ± 0.05 | 7.30 ± 0.14 | 3.10 ± 0.07 | 1.03 ± 0.10 | 7.42 ± 0.34 | 3.12 ± 0.03 |
Low(n = 4) | 1.00 ± 0.03 | 7.47 ± 0.38 | 3.13 ± 0.09 | 1.06 ± 0.10 | 7.34 ± 0. 17 | 3.19 ± 0. 03 |
Control(n = 6) | 1.05 ± 0.06 | 7.31 ± 0.25 | 3.08 ± 0.10 | 1.15 ± 0.08 | 7.37 ± 0.28 | 3.17 ± 0.10 |
Day 90 | ||||||
High (n = 6) | 1.09 ± 0.05 | 7.46 ± 0.42 | 3.13 ± 0.12 | 1.06 ± 0.03 | 7.26 ± 0.53 | 3.13 ± 0.07 |
Middle (n = 4) | 1.13 ± 0.10 | 7.19 ± 0.12 | 3.05 ± 0.13 | 1.08 ± 0.06 | 7.31 ± 0.33 | 3.11 ± 0.09 |
Low(n = 4) | 1.04 ± 0.07 | 7.55 ± 0.35 | 3.15 ± 0.01 | 1.10 ± 0.07 | 7.58 ± 0.36 | 3.16 ± 0. 04 |
Control(n = 6) | 1.08 ± 0.07 | 7.39 ± 0.12 | 3.12 ± 0.10 | 1.18 ± 0.04 | 7.35 ± 0.25 | 3.13 ± 0.02 |
Day 118 | ||||||
High (n = 2) | 1.10 ± 0 | 7.48 ± 0.12 | 3.08 ± 0.06 | 1.03 ± 0.06 | 7.29 ± 0.80 | 3.17 ± 0.04 |
Control(n = 2) | 1.08 ± 0.07 | 7.35 ± 0.30 | 3.08 ± 0.06 | 1.09 ± 0.01 | 7.74 ± 0.01 | 3.15 ± 0.02 |