Fig. 7From: Congenital goiter with areas of signet ring cell differentiation in a juvenile giraffe: a very rare entityHistopathological features of the thyroid. The HFCs were large in size. Obvious vacuoles and oval eccentric nuclei are visible in the cell cytoplasm. The whole cells showed signet-ring simulation (blue arrow). Numerous signet-ring-like HFCs are lined on the basement membrane of the thyroid follicles (left)Back to article page