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Table 2 The MIC of Chol-37(F34-R) against bacteria

From: Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification

Bacteria Strains

MIC (μg/mL) a

PMAP-37

PMAP-37(F34-R)

Chol-37(F34-R)

S. aureus ATCC25923

0.0313

0.0156*

0.0078**

L. monocytogenes CICC21634

4

2*

0.5**

S. typhimurium SL1344

4

1**

0.5**#

P. aeruginosa GIM1.551

2

1*

0.5**

  1. aMinimum inhibitory concentration (MIC) was determined as the lowest concentration of peptide that inhibited bacterial growth, which was determined in three independent experiments performed in triplicate
  2. *, P < 0.05 and **, P < 0.01, compared with PMAP-37. #, P < 0.05, compared with PMAP-37(F34-R)