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Fig. 10 | BMC Veterinary Research

Fig. 10

From: Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification

Fig. 10

In vivo therapeutic effect of Chol-37(F34-R) against S. aureus ATCC25923 or P. aeruginosa GIM1.551-infected mouse abscess model. a shows typical photographs of S. aureus ATCC25923 or P. aeruginosa GIM1.551-infected abscess sites on day 3 after different treatments. b and c show the normalized number of viable S. aureus ATCC25923 or P. aeruginosa GIM1.551 isolated from abscess sites on day 3 after different treatments. BP, benzylpenicillin potassium. AS, ampicillin sodium. The data are presented as means ± SD of results (n = 5). The number of bacteria (CFU) in the PBS group was defined as 100%, and the other groups are displayed proportionally compared with the PBS group.*, P < 0.05 and **, P < 0.01, compared with PBS. ##, P < 0.01, compared with PMAP-37(F34-R). ns, nonsignificant difference

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