Fig. 5

CCM exosomes decrease ROS production in canine fibroblasts. a Canine fibroblast cell viability after exposure to 50,100,200 and 500 μM H₂O₂ for 3 h, 6 h and 24 h. b Fluorescence intensity equivalent to ROS generation by canine fibroblasts according to the applied treatment. Asterisks indicate significant differences between compared values P < 0.05 (*), P < 0.01 (**) and P < 0.001 (***). Data are expressed as the mean ± SD