Table 2 Antibacterial activity of the designed synthetic peptides against T. pyogenes and E. coli
Strain | Antibacterial index | Lfcin | Lfcin DB | Lfcin C36G |
|---|---|---|---|---|
Trueperella pyogenes isolate | MIC50 | 3.9 (1.2) | 3.9 (1.2) | 7.8 (2.5) |
MIC90 | 7.8 (2.5) | 3.9 (1.2) | 15.6 (5.0) | |
MBC | 7.8 (2.5) | 3.9 (1.2) | 15.6 (5.0) | |
Trueperella pyogenes ATCC 19,411 | MIC50 | 3.9 (1.2) | 3.9 (1.2) | 7.8 (2.5) |
MIC90 | 3.9 (2.5) | 3.9 (1.2) | 7.8 (5.0) | |
MBC | 7.8 (2.5) | 3.9 (1.2) | 15.6 (5.0) | |
Escherichia coli ATCC 25,922 | MIC50 | 62.5 (20.0) | 125.0 (40.0) | 125.0 (40.6) |
MIC90 | 62.5 (20.0) | 250.0 (80.0) | 125.0 (40.6) | |
MBC | 62.5 (20.0) | 250.0 (80.0) | 125.0 (40.6) |