Table 2 Overview of the fecal pharmacokinetic (PK) parameters

C_max (μg/g)

17.75 ± 3.64^a

5.11 ± 1.27^b

15.00 ± 4.01^a

24.14 ± 4.48^c

C_max/D

2.94 10^− 4 ±

1.59 10^{− 4 a}

2.6110^− 4 ±

7.42 10^{− 5 a}

3.67 10⁻⁴ ±

1.07 10^{− 4 a}

2.97 10^− 4 ±

1.17 10^{− 4 a}

C_min (μg/g)

6.53 ± 4.96^a

4.32 ± 1.51^a

5.21 ± 4.97^a

7.92 ± 4.01^a

AUC_0–58hfeces

(h*μg/g)

775.93 ± 217.80^a

299.34 ± 55.55^b

808.01 ± 122.33^a

1469.61 ± 502.00^c

C_ssfeces (μg/g)

12.94 ± 0.55^a

4.51 ± 1.28^b

10.64 ± 2.32^a

19.53 ± 11.96^c