Fig. 1
From: Disseminated Scedosporium apiospermum infection in a Maremmano-Abruzzese sheepdog
Inguinal subcutaneous tissue, dog. a Two pyogranulomas with a “target-like” appearance are visible in the deep subcutis near the mammary gland. The centers of the granulomas are necrotic (black asterisks). The peripheral zones are filled with irregularly arranged macrophages and lymphocytes. Hematoxylin and Eosin (HE) staining. b A multinucleated giant cell (black arrow) is observed near the necrotic core of the pyogranuloma. HE staining. c Periodic acid-Schiff staining showed PAS-positive structures with parallel walls and dichotomous branching. d Irregular fungal black hyphae are visible. Grocott staining