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Fig. 2 | BMC Veterinary Research

Fig. 2

From: The pathogenesis of a North American H5N2 clade 2.3.4.4 group A highly pathogenic avian influenza virus in surf scoters (Melanitta perspicillata)

Fig. 2

Histopathology and immunohistochemical detection of influenza virus antigen in tissues from Surf Scoters inoculated with A/Northern pintail/Washington/40964/2014 (H5N2) HPAIV. a Cerebrum. Congestion and necrosis. Inset: virus antigen in neurons and glial cells (red staining), 20X magnification. b Pancreas. Acinar cell degeneration and necrosis. Inset: virus antigen in acinar cells and mononuclear cells (red staining), 40X magnification. c Spleen. Parenchymal cell degeneration and necrosis with accumulation of proteinaceous, fibrin-like material, 40X magnification. d Spleen. Presence of basophilic intranuclear inclusion bodies in reticular endothelial cells (arrows), 60X magnification. e Liver. Hepatocyte degeneration and necrosis and replacement with proteinaceous, fibrin-like material. f Liver. Presence of basophilic intranuclear inclusion bodies in hepatocytes (arrows), 60X magnification

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