TY - JOUR AU - Borghesi, Jéssica AU - Caceres, Sara AU - Mario, Lara Carolina AU - Alonso-Diez, Angela AU - Silveira Rabelo, Ana Carolina AU - Illera, Maria J. AU - Silvan, Gema AU - Miglino, Maria Angélica AU - Favaron, Phelipe O. AU - Carreira, Ana Claudia O. AU - Illera, Juan Carlos PY - 2020 DA - 2020/09/24 TI - Effects of doxorubicin associated with amniotic membrane stem cells in the treatment of canine inflammatory breast carcinoma (IPC-366) cells JO - BMC Veterinary Research SP - 353 VL - 16 IS - 1 AB - Tumours in mammary glands represent the most common neoplasia in bitches, as in humans. This high incidence results in part from the stimulation of sex hormones on these glands. Among mammary tumours, inflammatory carcinoma is the most aggressive, presenting a poor prognosis to surgical treatment and chemotherapy. One of the most widely used chemotherapy drugs for breast cancer treatment is doxorubicin (DOXO). Alternative therapies have been introduced in order to assist in these treatments; studies on treatments using stem cells have emerged, since they have anti-inflammatory and immunomodulatory properties. The aim of this study was to evaluate the effects of DOXO and canine amniotic membrane stem cells (AMCs) on the triple-negative canine inflammatory mammary carcinoma cell line IPC-366. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-020-02576-0 DO - 10.1186/s12917-020-02576-0 ID - Borghesi2020 ER -